Comparative dilator effect of verapamil and sodium nitroprusside in forearm arterial bed and dorsal hand veins in man: functional differences between vascular smooth muscle in arterioles and veins.
نویسندگان
چکیده
Verapamil and sodium nitroprusside induce a dose dependent dilatation in the forearm arterial bed and preconstricted dorsal hand vein in man. Verapamil is about twenty times more effective in dilating arterioles than veins; sodium nitroprusside is about ten times more effective in veins than arterioles. These differences can be related to functional differences between the two types of vessel.
منابع مشابه
Response of forearm resistance vessels to verapamil and sodium nitroprusside in normotensive and hypertensive men: evidence for a functional abnormality of vascular smooth muscle in primary hypertension.
1. The response of the forearm resistance vessels to local intra-arterial infusion of verapamil and sodium nitroprusside has been assessed by a plethysmographic method in 23 men with normal arterial pressure and 35 men with primary hypertension. 2. In the 20 patients with hypertension for whom full dose-response curves were determined, the dilator response to verapamil was significantly greater...
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عنوان ژورنال:
- Cardiovascular research
دوره 13 1 شماره
صفحات -
تاریخ انتشار 1979